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Molfinity

Leptomycin B - CAS 87081-35-4

Leptomycin B - CAS 87081-35-4

MF-0018805-01

$236.91 USD
$236.91 USD
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Product Details

  • Bioactivity

    Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue.

  • Target

    Antifungal, CRM1, Antibiotic

  • Related Pathways

    Membrane transporter/Ion channel, Microbiology/Virology

  • CAS Number

    87042

  • Purity

    0.9971

  • Molecular Formula

    C33H48O6

  • Molecular Weight

    540.73

  • SMILES

    CC\C(\C=C\[C@H]1OC(=O)C=C[C@@H]1C)=C\[C@H](C)C\C=C\C(\C)=C\[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C\C(C)=C\C(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound