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Leptosphaerodione - CAS 138039-33-5
Leptosphaerodione - CAS 138039-33-5
SKU:MF-0155315-01
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Product Details
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Bioactivity
Leptosphaerodione, a compound derived from the Remotididymella sp. fungus, functions as a potent inhibitor of the ubiquitin-proteasome system (UPS) and demonstrates cytotoxic effects in HeLa cells with an IC50 value of 3.2 μM, classifying it as an anti-tumor agent [1].
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Target
Others, Proteasome
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Related Pathways
Others, Proteases/Proteasome, Ubiquitination
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CAS Number
138001
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Molecular Formula
C21H22O5
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Molecular Weight
354.4
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SMILES
OC1=C2C(=CC3=C1COC(\C(=C\C(CC)C)\C)=C3)C=C(OC)C(=O)C2=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product