Leriglitazone - CAS 146062-44-4

Leriglitazone, a metabolite of pioglitazone, binds to the PPARγ C-terminal ligand-binding domain (Ki: 1.2 μM) and induces transcriptional efficacy of the PPARγ (EC50: 680 nM) . Leriglitazone PioOH is a PPARγ agonist, stabilizes the PPARγ activation function-2 (AF-2) co-activator binding surface.

Others, PPAR

DNA Damage/DNA Repair, Metabolism, Others

146014

C19H20N2O4S

372.44

O=C1SC(C(=O)N1)CC2=CC=C(OCCC3=NC=C(C=C3)C(O)C)C=C2

-20°C

Ice Packs

Small Compound