Levosimendan - CAS 141505-33-1

Levosimendan (OR1259) is a calcium sensitizer used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart to calcium, thus increasing cardiac contractility without a rise in intracellular calcium. Levosimendan exerts its effect by increasing calcium sensitivity of myocytes by binding to cardiac troponin C in a calcium-dependent manner.

Potassium Channel, Carbonic Anhydrase, Autophagy, PDE

Metabolism, Membrane transporter/Ion channel, Autophagy

141471

0.9991

C14H12N6O

280.28

C[C@H]1C(C2=CC=C(NN=C(C#N)C#N)C=C2)=NNC(=O)C1

-20°C

Ice Packs

Small Compound