LGB321 monohydrochloride - CAS 1469925-36-7

LGB321 monohydrochloride is an effective, selective, and orally active ATP-competitive small molecule inhibitor that targets all three PIM kinases. It inhibits proliferation, the mTOR-C1 signaling pathway, and BAD phosphorylation in various blood cancer-derived cell lines. LGB321 monohydrochloride is suitable for research on hematological malignancies.

MTOR, Pim

JAK/STAT signaling, Chromatin/Epigenetic, PI3K/Akt/mTOR signaling

1469882

C23H23ClF3N5O2

493.91

N(C(=O)C=1N=C(C(F)=CC1)C2=C(F)C=CC=C2F)C=3C(=CC=NC3)N4C[C@H](C)[C@@H](O)[C@H](N)C4.Cl

-20°C

Ice Packs

Small Compound