LH2-051 - CAS 2358754-22-8

LH2-051 is a lysosomal-enhancing lead compound that stimulates lysosomal biosynthesis and the clearance of Aβ aggregates through the dopamine transporter-cell cycle protein dependent kinase 9-transcription factor EB (DAT-CDK9-TFEB) pathway. Demonstrating favorable pharmacokinetic properties in mouse models, LH2-051 has the potential to improve Alzheimer's disease outcomes.

Dopamine Receptor, CDK

Cell Cycle/Checkpoint, Neuroscience, GPCR/G Protein

2358754-22-8

C27H34N2O3

434.57

O(C=1C=C2C(=CC1OC)C(N(CC2)CC3CCOCC3)CCC4=CNC=5C=CC=CC54)C

-20°C

Ice Packs

Small Compound