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Liarozole HCl - CAS 145858-50-0
Liarozole HCl - CAS 145858-50-0
SKU:MF-0138806-01
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$1,515.42 USD
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$1,515.42 USD
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Product Details
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Bioactivity
Liarozole HCl is a benzimidazole derivative with antineoplastic activity. As a retinoic acid metabolism blocking agent, liarozole inhibits CYP450-dependent all-trans-retinoic acid (ATRA) -4-hydroxylase, leading to an increase in endogenous ATRA production, inhibition of cell proliferation, and induction of cell differentiation. It also inhibits aromatase.
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Target
Others, Cytochromes P450, Retinoid Receptor
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Related Pathways
Others, Metabolism
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CAS Number
145808
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Molecular Formula
C17H14Cl2N4
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Molecular Weight
345.23
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SMILES
Cl.ClC1=CC=CC(=C1)C(C=2C=CC=3N=CNC3C2)N4C=NC=C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound