Licochalcone D - CAS 144506-15-0

Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotective potential against myocardial ischemia/reperfusion injury in langendorff-perfused rat hearts. Licochalcone D has anti-inflammatory activity, it shows suppression ability of nitric oxide (NO) production. Licochalcone D has anti-allergic activity, it suppresses degranulation by decreasing the intracellular Ca2+ level and tyrosine phosphorylation of ERK in RBL-2H3 cells.

NF-κB, Apoptosis, Reactive Oxygen Species, ERK, ROS

Metabolism, Apoptosis, Immunology/Inflammation, NF-κB, MAPK

144491

0.999

C21H22O5

354.4

COc1c(O)c(O)ccc1\C=C\C(=O)c1ccc(O)c(CC=C(C)C)c1

-20°C

Ice Packs

Natural Product