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Ligritinib - CAS 3024588-48-2

Ligritinib - CAS 3024588-48-2

SKU:MF-0118025-01

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  • Bioactivity

    Ligritinib (AB801) is an orally active inhibitor of the AXL receptor tyrosine kinase. By inhibiting the kinase activity of AXL, Ligritinib blocks its downstream signaling pathways. It is utilized in cancer research, particularly in studies involving non-small cell lung cancer (NSCLC) in combination with chemotherapy.

  • Target

    TAM Receptor

  • Related Pathways

    Tyrosine Kinase/Adaptors

  • CAS Number

    3024538

  • Molecular Formula

    C33H32N6O

  • Molecular Weight

    528.65

  • SMILES

    CC1=C(C2=CC=C(C=3C4=CC(C=5C=C6CC[C@@H](N7C8CC7COC8)CCC6=CC5)=CN=C4NN3)N=C2)N=CC=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound