Linsidomine hydrochloride - CAS 16142-27-1

Linsidomine hydrochloride (SIN-1 chloride) is considered as a metabolite of moxidomine, with vasodilation, inhibition of platelet aggregation, and antiangina activity. In myocardial ischemia-reperfusion models, Linsidomine hydrochloride to reduce myocardial necrosis and reperfusion induced endothelial dysfunction is associated with the cavernosal mechanism of action involved in nitric oxide release.

Drug Metabolite, ROS, Autophagy, NF-κB, Apoptosis, Annexin A

GPCR/G Protein, Immunology/Inflammation, Apoptosis, Metabolism, Autophagy, NF-κB

16114

0.9981

C6H11ClN4O2

206.63

Cl.NC1=CN(NO1)N1CCOCC1

-20°C

Ice Packs

Small Compound