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Molfinity

Lithocholic acid - CAS 434-13-9

Lithocholic acid - CAS 434-13-9

SKU:MF-0093138-01

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  • Bioactivity

    Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM), EphA2 antagonists (IC50=48, 66 μM) and EphB4 antagonists (IC50=141 μM) . Lithocholic acid can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is a cleanser that dissolves fat for absorption and is itself absorbed.

  • Target

    Endogenous Metabolite, Autophagy, Apoptosis, FXR

  • Related Pathways

    Metabolism, Apoptosis, Autophagy

  • CAS Number

    412

  • Purity

    0.9998

  • Molecular Formula

    C24H40O3

  • Molecular Weight

    376.57

  • SMILES

    [H][C@@]12CC[C@H]([C@H](C)CCC(O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product