Litoxetine - CAS 86811-09-8

Litoxetine is a selective 5-HT uptake inhibitor and is a 5-HT3 receptor antagonist. Litoxetine acts as an antidepressant and has shown antiemetic properties in ferrets. Litoxetine (1 and 10 mg/kg i.v.) dose-dependently reduced the number of regurgitations and vomiting and delayed the onset of vomiting. Litoxetine has an affinity for brain 5HT3 receptors (Ki = 85 nM) .

5-HT Receptor

Neuroscience, GPCR/G Protein

86811-09-8

0.9968

C16H19NO

241.33

C(OC1CCNCC1)C2=CC3=C(C=C2)C=CC=C3

-20°C

Ice Packs

Small Compound