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Molfinity

LLW-018 - CAS 3049369-11-8

LLW-018 - CAS 3049369-11-8

SKU:MF-0117606-01

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  • Bioactivity

    LLW-018 is a potent PD-1/PD-L1 inhibitor with an IC50 value of 2.61 nM. It can disrupt the PD-1/PD-L1 interaction, with a cell-based PD-1/PD-L1 blocking bioassay IC50 value of 0.88 μM. LLW-018 holds potential for research in immune-related diseases.

  • Target

    PD-1/PD-L1

  • Related Pathways

    Apoptosis, Cell Cycle/Checkpoint, Immunology/Inflammation

  • CAS Number

    3049350

  • Molecular Formula

    C35H38Cl2N4O5S

  • Molecular Weight

    697.67

  • SMILES

    ClC1=CC(=CC=C1OCC=2C=CC=C(C=3C=CC=C4C(=NSC43)NC5=CC=C(C=C5Cl)CNC(CO)CO)C2C)CNC(CO)CO

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound