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LLY-283 - CAS 2040291-27-6
LLY-283 - CAS 2040291-27-6
SKU:MF-0033192-01
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Product Details
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Bioactivity
LLY-283 is a potent, selective, and oral protein arginine methyltransferase 5 (PRMT5) inhibitor, exhibiting an IC50 of 22 nM and a Kd of 6 nM for the PRMT5:MEP50 complex, and demonstrates antitumor activity.
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Target
Histone Methyltransferase
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Related Pathways
Chromatin/Epigenetic
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CAS Number
2040258
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Purity
0.9949
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Molecular Formula
C17H18N4O4
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Molecular Weight
342.35
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SMILES
[H][C@@]1(O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(N)ncnc12)[C@H](O)c1ccccc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound