LM-021 - CAS 1022282-98-9

LM-021, a coumarin-chalcone derivative, exhibits properties such as anti-aggregation, antioxidant, neuroprotective, and anti-inflammatory effects. It inhibits the production of nitric oxide (NO), IL-1β, IL-6, and TNF-α, as well as the expression of CD68 and MHCII. Additionally, LM-021 reduces caspase 1 activity, lactate dehydrogenase release, and ROS level elevation. It is used in neurological research.

Interleukin, Reactive Oxygen Species, Dehydrogenase, Caspase

Metabolism, Immunology/Inflammation, Proteases/Proteasome, Apoptosis, NF-κB

1022175

C20H17NO4

335.35

OC=1C=2C(OC(=O)C1C(/C=C/C3=CC=C(N(C)C)C=C3)=O)=CC=CC2

-20°C

Ice Packs

Small Compound