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LMP517 - CAS 1883730-99-1

LMP517 - CAS 1883730-99-1

MF-0120866-01

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Product Details

  • Bioactivity

    LMP517 (NSC 781517), an indenoisoquinoline, is a potent dual TOP1 and TOP2 inhibitor that shows better antitumor activity than its parent compound LMP744 against H82 (Small Cell Lung Cancer) xenografts, inducing TOP1 cleavage complexes (TOP1ccs) and TOP2ccs [1].

  • Target

    Topoisomerase

  • Related Pathways

    DNA Damage/DNA Repair

  • CAS Number

    1883730-99-1

  • Molecular Formula

    C22H19FN2O5

  • Molecular Weight

    410.4

  • SMILES

    C(CCNCCO)N1C2=C(C=3C(C1=O)=CC(F)=CC3)C(=O)C=4C2=CC5=C(C4)OCO5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound