LNK01004 - CAS 2445500-24-1

LNK01004 is a JAK inhibitor that exhibits potent inhibitory effects on JAK1 (IC50: 10 nM), JAK2 (IC50: <0.51 nM), and TYK2 (IC50: 1.0 nM) . It can concurrently inhibit multiple cytokine-induced p-STAT signaling pathways and is applicable for research on diseases such as atopic dermatitis.

JAK, STAT

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Stem Cells, Angiogenesis

2445475

C26H31N7O2

473.57

N#CCNC(=O)C=1C=CC(=CC1)C2=NC(=NC=C2C)NC=3C=NN(C3)C4CC(OC(C)(C)C4)(C)C

-20°C

Ice Packs

Small Compound