LNSMGQD - CAS 1152066-26-6

LNSMGQD is a peptide that targets the adhesive interfaces of desmoglein (DSG1 and DSG3) core glycoproteins, interfering with the single peptide (SP) components of DSG trans-interactions. By binding to DSGs, LNSMGQD prevents the loss of DSG trans-interactions induced by autoantibodies, inhibits the activation of p38 MAPK, and prevents keratin filament retraction. It is useful for research into autoimmune skin diseases such as pemphigus vulgaris.

P38 MAPK

MAPK

1152066-26-6

C29H49N9O13S

763.82

[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC(O)=O)C(O)=O)=O)CCC(N)=O)=O)=O)CCSC)=O)CO)=O)(NC([C@H](CC(C)C)N)=O)CC(N)=O

-20°C

Ice Packs

Peptide