Lomitapide - CAS 182431-12-5

Lomitapide (AEGR-733) is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) in the assembly of very-low-density lipoprotein.

Others, MTP, MTP

Others, Proteases/Proteasome, Metabolism

182414

>99.99%

C39H37F6N3O2

693.72

FC(F)(F)CNC(=O)C1(CCCCN2CCC(CC2)NC(=O)c2ccccc2-c2ccc(cc2)C(F)(F)F)c2ccccc2-c2ccccc12

-20°C

Ice Packs

Small Compound