Lonitoclax - CAS 2952589-57-8

Lonitoclax is an inhibitor of B-cell lymphoma 2 (Bcl-2) . It demonstrates antitumor activity in B-cell and myeloid malignancy models comparable to Venetoclax. Lonitoclax holds potential for research in relapsed or refractory chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma, and certain low-grade lymphomas.

Bcl-2 Family

Apoptosis

2952524

C43H45ClN4O5

733.294

C(=O)(C1=C(C=C(Cl)C=C1)C2=CC(C(N(CC3=C(C)C(OC)=CC=C3)C4=CC=C(O)C=C4)=O)=C(C)N2C)N5[C@H](CN6CCOCC6)CC=7C(C5)=CC=CC7

-20°C

Ice Packs

Small Compound