Lopinavir-d8 - CAS 1322625-54-6

Lopinavir-d8 is a deuterated compound of Lopinavir. Lopinavir has a CAS number of 192725-17-0. Lopinavir is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins than the structurally-related drug ritonavir.

HIV Protease, SARS-CoV

Microbiology/Virology, Proteases/Proteasome

1322625-54-6

C37H40D8N4O5

636.85

C(C(N[C@@H](CC1=CC=CC=C1)C[C@@H]([C@H](CC2=CC=CC=C2)NC(COC3=C(C)C=CC=C3C)=O)O)=O)(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])(N4C(=O)NCCC4)[2H]

-20°C

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