Loureirin A - CAS 119425-89-7

Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related peptide (CRP), ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs) -seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4, inhibiting the synthesis and secretion of α- SMA, TGF- β1and the proliferation of HSCs.

PI3K, Akt

Cytoskeletal Signaling, PI3K/Akt/mTOR signaling

119329

0.9997

C17H18O4

286.32

COc1ccc(CCC(=O)c2ccc(O)cc2)c(OC)c1

-20°C

Ice Packs

Natural Product