Lp (a) -IN-5 hydrochloride - CAS 2924841-80-3

Lp (a) -IN-5 (Compound A) hydrochloride is an orally active inhibitor of lipoprotein (a) [Lp (a) ]. It effectively inhibits the assembly of Apo (a) and ApoB proteins with an IC50 value of 0.41 nM. This compound shows potential for research in diseases related to elevated plasma Lp (a) levels, such as cardiovascular disorders.

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2924758

C43H60Cl4N4O7

886.77

OC([C@H]([C@@]1([H])CCNC1)CC2=CC(CN(CCOC3=CC(C[C@@H]([C@@]4([H])CCNC4)C(O)=O)=CC=C3)CC5=CC(C[C@@H]([C@@]6([H])CCNC6)C(O)=O)=CC=C5)=CC=C2)=O.Cl.Cl.Cl.Cl

-20°C

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Small Compound