LPT99 - CAS 1263477-83-3

LPT-99 is an antagonist of the apoptosis protease-activating factor 1 (APAF-1) . It inhibits the activation of procaspase-9 and can suppress apoptosis induced by Cisplatin. Additionally, LPT-99 effectively reduces Cisplatin-induced hearing loss in rats.

Apoptosis, Caspase

Apoptosis, Proteases/Proteasome

1263391

C31H32Cl2N4O4S

627.581

O=C(NCCC1=CNC=2C=CC(OC)=CC21)CC3C(=O)N(CC(=O)N3CCC=4SC=CC4)CCC5=CC=C(Cl)C=C5Cl

-20°C

Ice Packs

Small Compound