LRRK2-IN-10 - CAS 2704562-80-9

LRRK2-IN-10 (compound 34) is a potent, mutation-selective, brain-penetrant inhibitor targeting G2019S-LRRK2 kinase with IC50 values of 11 nM for G2019S-LRRK2 pS935 and 5.2 nM for G2019S-LRRK2 pS1292, holding promise for research into Parkinson's disease [1].

LRRK2

Autophagy

2704473

C20H15N5O

341.37

N(C=1C=C2C(=NNC2=CC1)C=3C=NOC3)[C@@H]4C=5C(CC4)=CC(C#N)=CC5

-20°C

Ice Packs

Small Compound