LRRK2-IN-12 - CAS 3032733-05-1

LRRK2-IN-12 (compound 1) is a potent inhibitor of LRRK2 (G20195) with an IC 50 of 0.45 nM, LRRK2 WT with an IC 50 of 1.1 nM, and LRRK2 WT ADP-Glo with an IC 50 of 0.46 nM. This compound is utilized in research related to Alzheimer's Disease [1].

LRRK2

Autophagy

3032733-05-1

C18H17ClN8O2

412.83

ClC=1C2=C3N(N1)CCCOC=4C(N=C(N3)N=C2)=C(C)N(N4)C5=C(OC)N=CC=C5

-20°C

Ice Packs

Small Compound