1 1

Molfinity

LRRK2-IN-14 - CAS 2942328-06-3

LRRK2-IN-14 - CAS 2942328-06-3

MF-0120874-01

$0.00 USD
$0.00 USD
Sale Sold out
Taxes included.
Size
View full details

Product Details

  • Bioactivity

    LRRK2-IN-14 (Compound 8), an orally active inhibitor of LRRK2, exhibits an IC 50 of 6.3 nM against LRRK2 (G2019S) cell activity and demonstrates inhibitory effects on hERG with an IC 50 of 22 μM. Additionally, LRRK2-IN-14 is permeable to the blood-brain barrier [1].

  • Target

    LRRK2

  • Related Pathways

    Autophagy

  • CAS Number

    2942328-06-3

  • Molecular Formula

    C17H18F3N5O2

  • Molecular Weight

    381.35

  • SMILES

    O(C)C1=C2NC=3NC(C(C(F)(F)F)=CN3)=NCCCN(C)C(=O)C(=C2)C=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound