LRRK2-IN-17 - CAS 2101821-86-5

LRRK2-IN-17 is an orally active LRRK2 inhibitor with IC50 values of 3.5 nM for WT and 3.3 nM for G2019S, and it also inhibits RET kinase with an IC50 of 59 nM. LRRK2-IN-17 is utilized in research related to cancer and Parkinson's disease (PD) .

C-RET, LRRK2

Apoptosis, Tyrosine Kinase/Adaptors, Autophagy

2101730

C18H18N8

346.39

N(C1=C2C(=NC(NC=3N=NN(C)C3)=N1)NC=C2)[C@@H]4C=5C(CC4)=CC=CC5

-20°C

Ice Packs

Small Compound