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LRRK2/NUAK1/TYK2-IN-1 - CAS 2629192-96-5
LRRK2/NUAK1/TYK2-IN-1 - CAS 2629192-96-5
SKU:MF-0146178-01
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$1,383.80 USD
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Product Details
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Bioactivity
LRRK2/NUAK1/TYK2-IN-1 (compound 226) exhibits inhibitory activity against LRRK2 (Wt), LRRK2 (G2019), TYK2, and NUAK1, demonstrating IC50 values below 10 nM. This compound is useful for research into autoimmune diseases.
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Target
LRRK2, JAK, AMPK, Others
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Related Pathways
JAK/STAT signaling, Stem Cells, Others, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, Autophagy, Angiogenesis
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CAS Number
2629091
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Molecular Formula
C20H11F3N6
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Molecular Weight
392.34
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SMILES
FC=1C=C2C=3C(NC(=NC2=CC1C=4C=CN=NC4)C5=C(F)C=CC=C5F)=CNN3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound