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Molfinity

LS-102 - CAS 1456891-34-1

LS-102 - CAS 1456891-34-1

SKU:MF-0022810-01

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  • Bioactivity

    LS-102 is a selective inhibitor of the E3 ligase synoviolin (Syvn1), an astragaloside IV derivative, which attenuates myocardial ischemia/reperfusion injury by inhibiting mitochondrial fission.LS-102 inhibits Syvn1 auto-ubiquitylation, which ameliorates amyloidazole-induced slowing of the heart rate, and is useful for studying cardiovascular diseases.

  • Target

    Ligand for E3 Ligase, E1/E2/E3 Enzyme

  • Related Pathways

    Ubiquitination, PROTAC

  • CAS Number

    1456856

  • Purity

    0.9892

  • Molecular Formula

    C24H36N8O

  • Molecular Weight

    452.6

  • SMILES

    CCNCCN(CC)c1nc(N[C@@H](C)C2CCCCC2)nc(Nc2ccc3ncoc3c2)n1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound