LSD1/HDAC6-IN-2 - CAS 2982787-50-6

LSD1/HDAC6-IN-2 (JBI-802) is an orally active inhibitor of LSD1/HDAC6/HDAC8 with IC50 values of 50 nM, 11 nM, and 98 nM respectively, exhibiting good selectivity towards MAOs. JBI-802 demonstrates antiproliferative activity against multiple cell lines including AML, CLL, and SCLC, inhibiting tumour growth.

MAO, HDAC

Neuroscience, DNA Damage/DNA Repair, Chromatin/Epigenetic, Metabolism

2982787-50-6

C21H23BrN4O2

443.34

N(CC1=CN(CC2=CC=C(C(NO)=O)C=C2)N=C1)[C@H]3[C@@H](C3)C4=CC=CC=C4.Br

-20°C

Ice Packs

Small Compound