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LSKL TFA - CAS 2828433-17-4

LSKL TFA - CAS 2828433-17-4

SKU:MF-0045524-01

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  • Bioactivity

    LSKL TFA (H-Leu-Ser-Lys-Leu-NH2 TFA) is a LAP-TGFβ derivative and a TGF-β1 antagonist that can cross the blood-brain barrier, inhibits the binding of TSP-1 to LAP and reduces renal interstitial fibrosis and liver fibrosis, inhibits subarachnoid fibrosis by inhibiting TSP-1-mediated TGF-β1 activity, prevents the occurrence of chronic hydrocephalus and improves long-term neurocognitive deficits after subarachnoid hemorrhage.

  • Target

    TGF-beta/Smad

  • Related Pathways

    Stem Cells

  • CAS Number

    2828412

  • Purity

    0.9933

  • Molecular Formula

    C23H43F3N6O7

  • Molecular Weight

    572.62

  • SMILES

    O=C(O)C(F)(F)F.CC(C)C[C@@H](C(N)=O)NC([C@H](CCCCN)NC([C@H](CO)NC([C@@H](N)CC(C)C)=O)=O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide