LSN2814617 - CAS 1313498-17-7

LSN2814617 is an orally active, potent, brain-penetrant, and selective mGlu 5 (metabotropic glutamate 5) positive allosteric modulator (PAM), with EC 50 values of 52 nM (Human mGlu5) and 42 nM (rat mGlu5) . In vivo EEG studies demonstrated that LSN2463359 has marked wake-promoting properties with minimal rebound hypersomnolence, and it can be used for schizophrenia research [1].

Others, GluR

Others, Neuroscience

1313474

C18H20FN5O

341.38

C(C)(C)(C)C=1N2C(C[C@H](CC2)C3=NC(=NO3)C4=CC=C(F)C=C4)=NN1

-20°C

Ice Packs

Small Compound