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LSN2839567 - CAS 1231930-57-6

LSN2839567 - CAS 1231930-57-6

MF-0004288-01

$48.87 USD
$48.87 USD
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Product Details

  • Bioactivity

    LSN2839567 (Abemaciclib metabolite M2) is the active metabolite of Abemaciclib, a potent CDK4 and CDK6 inhibitor (IC50s: 1-3 nM) with anticancer activity.LSN2839567 inhibits CDK9.LSN2839567 inhibits cell growth and cell cycle progression in a concentration-dependent manner. cell growth and cell cycle progression in a concentration-dependent manner and can be used to study breast and lung cancer.

  • Target

    Drug Metabolite, CDK

  • Related Pathways

    Metabolism, Cell Cycle/Checkpoint

  • CAS Number

    1231867

  • Purity

    0.9914

  • Molecular Formula

    C25H28F2N8

  • Molecular Weight

    478.54

  • SMILES

    CC(C)n1c(C)nc2c(F)cc(cc12)-c1nc(Nc2ccc(CN3CCNCC3)cn2)ncc1F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound