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LSN3106729 hydrochloride - CAS 2704316-82-3
LSN3106729 hydrochloride - CAS 2704316-82-3
SKU:MF-0094127-01
Regular price
$305.35 USD
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$305.35 USD
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Product Details
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Bioactivity
LSN3106729 hydrochloride, the metabolite of Abemaciclib , is a CDK inhibitor with antitumor activity. LSN3106729 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[1].
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Target
Others, Ligands for Target Protein for PROTAC, CDK
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Related Pathways
PROTAC, Others, Cell Cycle/Checkpoint
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CAS Number
2704231
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Molecular Formula
C25H29ClF2N8O
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Molecular Weight
531
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SMILES
Cl.FC=1C=NC(=NC1C=2C=C(F)C=3N=C(N(C3C2)C(C)C)CO)NC4=NC=C(C=C4)CN5CCNCC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC