LTD4 antagonist 2 - CAS 107813-86-5

LTD4 antagonist 2 (compound 6) functions as a leukotriene D4 (LTD4) antagonist with an IC50 of 2.8 μM for the cysteinyl leukotriene 1 receptor (CysLT1R) . Additionally, it acts as an agonist for the G protein-coupled bile acid receptor 1 (GPBAR1), making it applicable for research into colitis, metabolic syndrome, and other GPBAR1- and CysLT1R-related diseases.

Leukotriene Receptor

GPCR/G Protein

107722

C17H13NO3

279.29

O=C(O)C=1C=CC=C(OCC2=NC=3C=CC=CC3C=C2)C1

-20°C

Ice Packs

Small Compound