LU-005i - CAS 1620107-33-6

LU-005i is a powerful inhibitor targeting the β5i subunit of immunoproteasomes, displaying a high potency with an IC 50 value of 6.6 nM, and exhibits selectivity by preferring β5i over the β5c subunit, which has an IC 50 value of 287 nM [1].

Others, Proteasome

Others, Proteases/Proteasome, Ubiquitination

1620107-33-6

C31H46N4O7

586.72

C([C@H](CC1CCCCC1)NC([C@H](CC2=CC=C(OC)C=C2)NC([C@@H](NC(CN3CCOCC3)=O)C)=O)=O)(=O)[C@@]4(C)CO4

-20°C

Ice Packs

Small Compound