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Molfinity

Lu AE98134 - CAS 849000-18-6

Lu AE98134 - CAS 849000-18-6

SKU:MF-0140750-01

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  • Bioactivity

    Lu AE98134, an activator of voltage-gated sodium channels, acts as a partly selective positive modulator of Nav1.1 channels and also increases the activity of Nav1.2 and Nav1.5 channels while not affecting Nav1.4, Nav1.6, and Nav1.7 channels. Lu AE98134 can be used to analyze pathophysiological functions of the Nav1.1 channel in various central nervous system diseases, including cognitive restoring in schizophrenia, et al[1].

  • Target

    Others, Sodium Channel

  • Related Pathways

    Others, Membrane transporter/Ion channel

  • CAS Number

    848976

  • Molecular Formula

    C21H23N5O3S

  • Molecular Weight

    425.5

  • SMILES

    CCCCNS(=O)(=O)c1ccc(OC)c(c1)-c1nnc2c3ccccc3c(C)nn12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound