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Lugdunin - CAS 1989698-37-4
Lugdunin - CAS 1989698-37-4
SKU:MF-0157673-01
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Product Details
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Bioactivity
Lugdunin is an antibiotic peptide that disrupts membrane potential in bacteria, demonstrating activity against Gram-positive species including S. aureus, and effectively reducing skin and nasal colonization of this pathogen. Moreover, Lugdunin stimulates the production of LL-37 and CXCL8/MIP-2 in human keratinocytes and mouse skin [1].
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Target
Antibacterial, Antibiotic
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Related Pathways
Microbiology/Virology
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CAS Number
1989657
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Molecular Formula
C40H62N8O6S
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Molecular Weight
783.04
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SMILES
C(C=1C=2C(NC1)=CC=CC2)[C@H]3C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@H]([C@@H](C)C)C(=O)N[C@@H](C(C)C)C4(N[C@](C(=O)N[C@H]([C@H](C)C)C(=O)N3)(CS4)[H])[H]
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide