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Molfinity

Lumacaftor - CAS 936727-05-8

Lumacaftor - CAS 936727-05-8

SKU:MF-0094526-01

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  • Bioactivity

    Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM) .

  • Target

    Autophagy, CFTR

  • Related Pathways

    Membrane transporter/Ion channel, Autophagy

  • CAS Number

    936727-05-8

  • Purity

    0.9972

  • Molecular Formula

    C24H18F2N2O5

  • Molecular Weight

    452.41

  • SMILES

    Cc1ccc(NC(=O)C2(CC2)c2ccc3OC(F)(F)Oc3c2)nc1-c1cccc(c1)C(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound