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LVTX-8 - CAS 2197957-07-4

LVTX-8 - CAS 2197957-07-4

SKU:MF-0127305-01

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  • Bioactivity

    LVTX-8 is a peptide toxin extracted from Lycosa vittata. It exhibits potent anticancer and antimetastatic effects against lung cancer, with strong cytotoxicity. LVTX-8 significantly induces apoptosis via the P53 hypoxia pathway and integrin signaling, inhibiting proliferation, invasion, and migration of lung cancer cells. It markedly suppresses tumor growth and metastasis in A549/H460 xenograft mouse models.

  • Target

    Apoptosis, MDM-2/p53, Integrin

  • Related Pathways

    Apoptosis, Cytoskeletal Signaling

  • CAS Number

    2197957-07-4

  • Molecular Formula

    C135H226N36O31

  • Molecular Weight

    2849.46

  • SMILES

    C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CCCCN)=O)CO)=O)CC(C)C)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCCCN)=O)C)=O)CC(C)C)=O)=O)CCCCN)=O)=O)CC(C)C)=O)CC(N)=O)=O)CCCCN)=O)=O)CC(C)C)=O)=O)CCCCN)=O)CC(C)C)=O)C)=O)[C@@H](C)O)=O)CC(C)C)=O)NC([C@H]([C@H](CC)C)N)=O)C=3C=4C(NC3)=CC=CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Peptide