LXG6403 - CAS 315705-04-5

LXG6403 is a powerful dual-thiazole LOX cell activity inhibitor with an IC50 of 1.3 μM. It exhibits anticancer properties by restructuring the extracellular matrix, enhancing the penetration of chemotherapeutic drugs, inducing reactive oxygen species (ROS) production, and promoting cell death mediated by DNA damage, thereby overcoming chemotherapy resistance in triple-negative breast cancer.

Others, ROS, Apoptosis, FAK, Lipoxygenase

Immunology/Inflammation, Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Metabolism, Others

315705-04-5

C15H15N5OS2

345.44

O=C(NC1=CC=C(C=C1)NC2=NC(=CS2)C=3SC(=NC3C)N)C

-20°C

Ice Packs

Small Compound