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Molfinity

LY 3000328 - CAS 1373215-15-6

LY 3000328 - CAS 1373215-15-6

MF-0006529-01

$103.81 USD
$63.05 USD $103.81 USD
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Product Details

  • Bioactivity

    LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S with IC50 values ​​of 7.7 and 1.67 nM for human and mouse cathepsin S, respectively. LY 3000328 (Cathepsin S inhibitor) may slow or prevent abdominal aortic aneurysm (AAA) expansion and/or reduce the risk of AAA rupture by inhibiting cathepsin S-mediated degradation of extracellular matrix proteins, elastin and collagen.

  • Target

    Cysteine Protease

  • Related Pathways

    Proteases/Proteasome

  • CAS Number

    1373215-15-6

  • Purity

    0.9954

  • Molecular Formula

    C25H29FN4O5

  • Molecular Weight

    484.52

  • SMILES

    CNC(=O)O[C@H]1COc2ccc(cc2[C@@H]1NC(=O)c1ccc(F)cc1)N1CCN(CC1)C1COC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound