1 1

Molfinity

LY2811376 - CAS 1194044-20-6

LY2811376 - CAS 1194044-20-6

MF-0093922-01

$45.88 USD
$45.88 USD
Sale Sold out
Taxes included.
Size
View full details

Product Details

  • Bioactivity

    LY2811376, an orally available non-peptidic β-secretase (BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM) . It has 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases including pepsin, cathepsin D, or renin.

  • Target

    BACE, Beta-Secretase, Beta Amyloid

  • Related Pathways

    Neuroscience

  • CAS Number

    1194018

  • Purity

    0.9901

  • Molecular Formula

    C15H14F2N4S

  • Molecular Weight

    320.36

  • SMILES

    C[C@]1(CCSC(N)=N1)c1cc(c(F)cc1F)-c1cncnc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound