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LY3020371 hydrochloride - CAS 1377615-44-5

LY3020371 hydrochloride - CAS 1377615-44-5

MF-0022840-01

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Product Details

  • Bioactivity

    LY3020371 hydrochloride exerts an antidepressant-like signature in vivo. LY3020371 hydrochloride is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, potently blocks cAMP formation with IC50 of 16.2 nM.

  • Target

    GluR

  • Related Pathways

    Neuroscience

  • CAS Number

    1377566

  • Molecular Formula

    C15H16ClF2NO5S

  • Molecular Weight

    395.81

  • SMILES

    Cl.[H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)([C@H](CSc1ccc(F)c(F)c1)[C@H]2O)C(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound