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LY3056480 - CAS 2064292-78-8
LY3056480 - CAS 2064292-78-8
SKU:MF-0121908-01
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Product Details
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Bioactivity
LY3056480 is a γ-secretase inhibitor (GSI) that inhibits Notch signaling. It demonstrates potential in improving mild to moderate sensorineural hearing loss while maintaining a good safety and tolerance profile. Administered intratympanically, LY3056480 can induce hair cell regeneration and partial hearing restoration in mammals.
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CAS Number
2064292-78-8
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Molecular Formula
C23H28F3N3O4
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Molecular Weight
467.48
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SMILES
N(C([C@@H](NC(CCC(F)(F)F)=O)C)=O)[C@H]1C=2C(N3C(=CC1=O)C(C)(C)CC3)=CC(OC)=CC2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound