LY367385 hydrochloride - CAS 2829282-00-8

LY367385 hydrochloride is a potent and selective mGluR1a antagonist with an IC50 value of 8.8 μM for inhibiting quisqualate-induced phosphoinositide (PI) hydrolysis, showing significantly higher selectivity compared to its >100 μM IC50 value for mGlu5a. This compound exhibits neuroprotective, anticonvulsant, and antiepileptic effects [1] [2].

Others, GluR

Neuroscience, Others

2829282-00-8

C10H12ClNO4

245.66

[C@H](C(O)=O)(N)C1=C(C)C=C(C(O)=O)C=C1.Cl

-20°C

Ice Packs

Small Compound