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LY487379 - CAS 353231-17-1

LY487379 - CAS 353231-17-1

MF-0036751

$39.90 USD
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Product Details

  • Bioactivity

    LY487379 is a selective human mGluR2 positive allosteric modulator (PAM) that enhances glutamate-stimulated [35 S] GTPγS binding to mGlu2 receptors (EC50: 1.7 μM) and mGlu3 receptors (EC50 >10 μM) . LY487379 induces cognitive flexibility and behavioral inhibition in a rat model and can be used to study schizophrenia.

  • Target

    Others, GluR

  • Related Pathways

    Others, Neuroscience

  • CAS Number

    353231-17-1

  • Molecular Formula

    C21H19F3N2O4S

  • Molecular Weight

    452.45

  • SMILES

    COc1ccccc1Oc1ccc(cc1)N(Cc1cccnc1)S(=O)(=O)CC(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound