Lycopodine - CAS 466-61-5

Lycopodine, a bioactive compound derived from Lycopodium clavatum spores, effectively inhibits the proliferation of HeLa cells through the induction of apoptosis. This process is mediated by caspase-3 activation. In refractory prostate cancer cells, Lycopodine triggers apoptosis by modulating 5-lipoxygenase and depolarizing the mitochondrial membrane potential, without altering p53 activity.

Caspase, Apoptosis, Lipoxygenase

Apoptosis, Metabolism, Proteases/Proteasome

400

C16H25NO

247.38

O=C1[C@@]2([C@]34[C@@]([C@](C1)(C[C@@H](C)C3)[H])(CCC[N@]4CCC2)[H])[H]

-20°C

Ice Packs

Natural Product