LYRM03 - CAS 1820750-36-4

LYRM03 is an aminopeptidase inhibitor. LYRM03 is also an ubenimex derivative. LYRM03 attenuates LPS-induced acute lung injury in mice by suppressing the TLR4 signaling pathway. LYRM03 effectively attenuates LPS-induced ALI by inhibiting the expression of pro-inflammatory mediators and Myd88-dependent TLR4 signaling pathways in alveolar macrophages. LYRM03 may serve as a potential treatment for sepsis-mediated lung injuries.

Others

Others

1820710

C21H33N3O5

407.5

[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)(NC([C@H]([C@@H](CC1=CC=CC=C1)N)O)=O)C(C)C

-20°C

Ice Packs

Small Compound